CALPOL Six Plus Fastmelts 250 mg Paracetamol OrodispersibleTablets

*
General Sale: Non-prescription
  • Company:

    Kenvue
  • Status:

    Updated
  • Legal Category:

    Supply through general sale
  • Active Ingredient(s):

    *Additional information is available within the SPC or upon request to the company

Updated on 08 November 2024

File name

ie-leaflet-calpol-fastmelts-2370.pdf

Reasons for updating

  • Change to section 6 - marketing authorisation holder
  • Change to section 6 - marketing authorisation number
  • Change to section 6 - date of revision

Updated on 08 November 2024

File name

ie-spc-v15 calpol 6 plus fastmelts-2370.pdf

Reasons for updating

  • Change to section 7 - Marketing authorisation holder
  • Change to section 8 - Marketing authorisation number(s)
  • Change to section 10 - Date of revision of the text

Legal category:Supply through general sale

Updated on 19 December 2022

File name

ie-pil-clean-calpol six plus fastmelt.pdf

Reasons for updating

  • Change to section 6 - manufacturer
  • Change to section 6 - date of revision

Updated on 25 April 2022

File name

ie-pl-calpol-fastmelts-2110.pdf

Reasons for updating

  • Change to section 2 - what you need to know - warnings and precautions
  • Change to section 2 - interactions with other medicines, food or drink
  • Change to section 6 - date of revision

Updated on 25 April 2022

File name

ie-spc-v13-calpol 6 plus fastmelts-2210.pdf

Reasons for updating

  • Change to section 4.4 - Special warnings and precautions for use
  • Change to section 4.5 - Interaction with other medicinal products and other forms of interaction
  • Change to section 10 - Date of revision of the text

Legal category:Supply through general sale

Updated on 06 January 2022

File name

402537232_Calpol_360135F_EMEA_2021_00030121_001_r0.pdf

Reasons for updating

  • Change to section 6 - date of revision

Updated on 13 April 2021

File name

401570935_360135D_Leaflet_CalpolSixPlusFastmelts_12s_IE_r2.pdf

Reasons for updating

  • Change to section 2 - what you need to know - warnings and precautions
  • Change to section 6 - what the product looks like and pack contents
  • Change to section 6 - date of revision

Updated on 13 April 2021

File name

ie-spc-v12 calpol 6 plus fastmelts - 2092.pdf

Reasons for updating

  • Change to section 2 - Qualitative and quantitative composition
  • Change to section 4.4 - Special warnings and precautions for use
  • Change to section 10 - Date of revision of the text

Legal category:Supply through general sale

Updated on 12 December 2019

File name

ie-spc-v11 calpol 6 plus fastmelts - 2004.pdf

Reasons for updating

  • Change to section 4.8 - Undesirable effects
  • Change to section 10 - Date of revision of the text

Legal category:Supply through general sale

Updated on 11 November 2019

File name

CalpolSixPlusFastmelts- PIL 1936.pdf

Reasons for updating

  • Change to section 2 - what you need to know - warnings and precautions

Updated on 11 November 2019

File name

ie-spc-v10-calpol-fastmelts-1936.pdf

Reasons for updating

  • Change to section 4.6 - Pregnancy and lactation
  • Change to section 5.3 - Preclinical safety data
  • Change to section 10 - Date of revision of the text

Legal category:Supply through general sale

Updated on 03 April 2019

File name

ie-leaflet-Calpol6+Fastmelts-1806.pdf

Reasons for updating

  • Change to section 2 - what you need to know - contraindications
  • Change to section 2 - what you need to know - warnings and precautions
  • Change to section 4 - possible side effects
  • Change to section 6 - date of revision

Updated on 03 April 2019

File name

ie-spc v9 calpol 6+ fastmelts-1806.pdf

Reasons for updating

  • Change to section 4.2 - Posology and method of administration
  • Change to section 4.3 - Contraindications
  • Change to section 4.4 - Special warnings and precautions for use
  • Change to section 4.5 - Interaction with other medicinal products and other forms of interaction
  • Change to section 4.6 - Pregnancy and lactation
  • Change to section 4.8 - Undesirable effects
  • Change to section 4.9 - Overdose
  • Change to section 10 - Date of revision of the text

Legal category:Supply through general sale

Updated on 05 February 2019

File name

ie-pl Calpol Six Plus Fastmelts 1839.pdf

Reasons for updating

  • Change to section 6 - marketing authorisation holder

Updated on 05 February 2019

File name

ie-spc v8 Calpol Six Plus Fastmelts 1839.pdf

Reasons for updating

  • Change to section 7 - Marketing authorisation holder
  • Change to section 8 - Marketing authorisation number(s)

Legal category:Supply through general sale

Updated on 28 September 2018

File name

ie-spc proposed 1832.pdf

Reasons for updating

  • Change to section 3 - Pharmaceutical form
  • Change to section 10 - Date of revision of the text

Legal category:Supply through general sale

Updated on 28 June 2018

File name

17-0255_360135B_PIL_CalpolSixPlusFastmelts_12s_v9.pdf

Reasons for updating

  • Improved presentation of PIL

Updated on 28 July 2015

File name

PIL_10703_865.pdf

Reasons for updating

  • New PIL for new product

Updated on 28 July 2015

Reasons for updating

  • Change to side-effects
  • Change to date of revision
  • Addition of information on reporting a side effect.

Updated on 21 July 2015

Reasons for updating

  • New SPC for new product

Legal category:Supply through general sale

Updated on 21 July 2015

Reasons for updating

  • Change to section 4.3 - Contraindications
  • Change to section 4.4 - Special warnings and precautions for use
  • Change to section 4.5 - Interaction with other medicinal products and other forms of interaction

Legal category:Supply through general sale

Free text change information supplied by the pharmaceutical company

Section 4.3 - QRD wording implemented

Section 4.4 - the following warning has been added:

Serious skin reactions such as acute generalized exanthematous pustulosis (AGEP), Stevens - Johnson syndrome (SJS), and toxic epidermal necrolysis (TEN), have been reported very rarely in patients receiving paracetamol. Patients should be informed about the signs of serious skin reactions, and use of the drug should be discontinued at the first appearance of skin rash or any other sign of hypersensitivity.

Section 4.5 - the following text has been added
The anticoagulant effect of warfarin and other coumarins may be enhanced by prolonged regular use of paracetamol with increased risk of bleeding; occasional doses have no significant effect. 

Section 4.6 has been updated as follows:

There are no adequate and well-controlled clinical studies in pregnant or breastfeeding women. Epidemiological studies indicate that paracetamol, when taken as directed, does not adversely affect the pregnant mother or fetus.

 

Pregnancy

When given to the mother in labeled doses, paracetamol crosses the placenta into fetal circulation as early as 30 minutes after ingestion and is effectively metabolized by fetal sulfate conjugation. When taken as directed, paracetamol

does not adversely affect the pregnant mother or fetus

 

Breastfeeding

Paracetamol is excreted in breast milk in low concentrations (0.1% to 1.85% of the ingested maternal dose). Maternal ingestion of paracetamol in labeled doses does not present a risk to the nursing infant.



Section 4.8 & 4.9 have been updated with new information - please see revised SPC for details. Section 4.8 has also been updated with Adverse events reporting information

Section 5.1 - the following paragraph has been added

ATC Code: N02BE01 – Other analgesics and antipyretics

Paracetamol is a centrally acting, non-opiate, non-salicylate analgesic. Paracetamol is a clinically proven analgesic/antipyretic, and it is thought to produce analgesia by elevation of the pain threshold and antipyresis through action on the hypothalamic heat-regulating centre.  Single-dose studies (12.5 mg/kg) of paracetamol in febrile children showed an onset of fever reduction within 15 to 30 minutes. 

Updated on 19 January 2012

Reasons for updating

  • Change to section 4.2 - Posology and method of administration
  • Change to section 4.4 - Special warnings and precautions for use

Legal category:Supply through general sale

Free text change information supplied by the pharmaceutical company

Implementation of change(s) requested by the National Competent Authority following the assessment of the paracetamol pediatric dosing schedule (section 4.2) with subsequent changes to section 4.4 warnings and precautions.

Updated on 17 January 2012

Reasons for updating

  • Change to warnings or special precautions for use
  • Change to dosage and administration

Updated on 20 July 2010

Reasons for updating

  • Change due to user-testing of patient information

Updated on 12 May 2010

Reasons for updating

  • Change to packaging

Updated on 25 August 2008

Reasons for updating

  • Change to marketing authorisation holder

Updated on 19 May 2008

Reasons for updating

  • Change to section 1 - Name of medicinal product

Legal category:Supply through general sale

Free text change information supplied by the pharmaceutical company

From:
Calpol Fastmelts 250mg Paracetamol Orodispersible Tablets
To:
Calpol Six Plus Fastmelts 250mg Paracetamol Orodispersible Tablets

Updated on 19 September 2007

Reasons for updating

  • Change to section 6.1 - List of excipients

Legal category:Supply through general sale

Free text change information supplied by the pharmaceutical company

Section 6.1
 
"colloidal anhydrous silica" changed to "silica hydrophobic colloidal anhydrous"

Updated on 19 September 2007

Reasons for updating

  • Change of inactive ingredient

Updated on 28 August 2007

Reasons for updating

  • Change to section 6.1 - List of excipients
  • Change to section 6.4 - Special precautions for storage

Legal category:Supply through general sale

Free text change information supplied by the pharmaceutical company

Section 6.1 Excipenty name amended: Colloidal Anhydrous Silica.
Section 6.4 Deleted phrase "Do not store above 30C"

Updated on 20 December 2006

Reasons for updating

  • Change to section 1 - Name of medicinal product
  • Change to section 2 - Qualitative and quantitative composition
  • Change to section 3 - Pharmaceutical form
  • Change to section 6.1 - List of excipients

Legal category:Supply through general sale

Free text change information supplied by the pharmaceutical company

Section 1 - "Orodispersible" added to name
Section 2 - Excipients added
Section 3 - Description inserted
Section 6.1 -  E numbers added
 

Updated on 20 December 2006

Reasons for updating

  • Change of active ingredient
  • Change to date of revision
  • Correction of spelling/typing errors

Updated on 15 February 2006

Reasons for updating

  • New PIL for medicines.ie

Updated on 18 June 2003

Reasons for updating

  • New SPC for medicines.ie

Legal category:Supply through general sale