Depo-Medrone 40mg/ml 2ml vial

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Pharmacy Only: Prescription

Updated on 24 October 2024

File name

c Reg HCP leaflet DM 22_1 PIL DM 27_0 IE - Copy.pdf

Reasons for updating

  • Change to section 2 - what you need to know - warnings and precautions

Free text change information supplied by the pharmaceutical company

The PIL has been updated to reflect the SPC changes.

Updated on 24 October 2024

File name

c Reg SPC DM 26_0 2ml IE - Copy.pdf

Reasons for updating

  • Change to section 4.4 - Special warnings and precautions for use

Legal category:Product subject to medical prescription which may not be renewed (A)

Free text change information supplied by the pharmaceutical company

The SPC has been updated as follows:

Thyrotoxic Periodic Paralysis warning in section 4.4

Updated on 18 October 2024

File name

c Reg SPC DM 26_0 2ml IE - Copy.pdf

Reasons for updating

  • Change to section 7 - Marketing authorisation holder

Legal category:Product subject to medical prescription which may not be renewed (A)

Updated on 18 October 2024

File name

c Reg HCP leaflet DM 22_1 PIL DM 27_0 IE - Copy.pdf

Reasons for updating

  • Change to section 6 - marketing authorisation holder
  • Change to section 6 - date of revision
  • Change to MA holder contact details

Updated on 16 July 2024

File name

Clean REG SPC DM 25_0 2ML IE .pdf

Reasons for updating

  • Change to section 4.8 - Undesirable effects

Legal category:Product subject to medical prescription which may not be renewed (A)

Free text change information supplied by the pharmaceutical company

The SPC has been updated as follows:

Update section 4.8 to add (Flushing and injection pain flare)


Updated on 16 July 2024

File name

clean Reg HCP leaflet DM 22_1 PIL DM 26_0 IE - Copy.pdf

Reasons for updating

  • Change to section 4 - possible side effects
  • Change to section 6 - date of revision

Updated on 26 September 2023

File name

CleanRegSPC DM 241 2ml IE.pdf

Reasons for updating

  • Change to section 4.4 - Special warnings and precautions for use
  • Change to section 4.8 - Undesirable effects

Legal category:Product subject to medical prescription which may not be renewed (A)

Free text change information supplied by the pharmaceutical company

The SPC has been updated as follows:

Updated section 4.4 (TLS warning) AND 4.8 following CDS update.


Updated on 26 September 2023

File name

CleanRegHCPleafletDM221 PIL DM 252 IE1.pdf

Reasons for updating

  • Change to section 2 - what you need to know - warnings and precautions

Updated on 13 February 2023

File name

DEC202109158_Reg SPC DM 23_1 2ml IE clean.pdf

Reasons for updating

  • Document format updated

Legal category:Product subject to medical prescription which may not be renewed (A)

Updated on 12 February 2021

File name

DEC202109158_Reg HCP leaflet DM 22_1 PIL DM 24_1 IE clean.pdf

Reasons for updating

  • Change to section 1 - what the product is used for
  • Change to section 6 - date of revision
  • Change to information for healthcare professionals
  • Correction of spelling/typing errors

Updated on 11 February 2021

File name

DEC202109158_Reg SPC DM 23_1 2ml IE clean.pdf

Reasons for updating

  • Change to section 4.2 - Posology and method of administration

Legal category:Product subject to medical prescription which may not be renewed (A)

Updated on 10 December 2020

File name

DEC202082814_Reg SPC DM 22_1 2ml IE clean.pdf

Reasons for updating

  • Change to section 4.4 - Special warnings and precautions for use

Legal category:Product subject to medical prescription which may not be renewed (A)

Updated on 10 December 2020

File name

DEC202082814_Reg HCP leaflet DM 21_1 PIL DM 23_1 IE clean.pdf

Reasons for updating

  • Change to section 2 - excipient warnings
  • Change to section 4 - how to report a side effect
  • Change to section 6 - marketing authorisation holder
  • Change to section 6 - date of revision

Updated on 21 November 2019

File name

DEC201964950_Reg HCP leaflet DM 21_1 PIL DM 22_2 IE clean.pdf

Reasons for updating

  • Change to section 4 - possible side effects
  • Change to section 6 - date of revision

Updated on 21 November 2019

File name

DEC201964950_Reg SPC DM 21_2 2ml IE clean.pdf

Reasons for updating

  • Change to section 4.4 - Special warnings and precautions for use
  • Change to section 4.6 - Pregnancy and lactation
  • Change to section 4.8 - Undesirable effects
  • Change to section 5.3 - Preclinical safety data

Legal category:Product subject to medical prescription which may not be renewed (A)

Free text change information supplied by the pharmaceutical company

The SPC has been updated as follows: Update to section 4.4 to add more information about peritonitis; section 4.6 to add information on low birth weight, relationship to dose and impairment of fertility; section 4.8 to add peritonitis and anaphylactoid reaction as well as PT updates; and 5.3 to add information concerning impairment of fertility, carcinogenesis, mutagenesis, embryo-foetal lethality, and details from animal studies.

Updated on 14 May 2019

File name

DEC201925046_Reg HCP leaflet DM 20_1 PIL DM 21_1 IE clean.pdf

Reasons for updating

  • Change to section 6 - manufacturer
  • Change to section 6 - date of revision

Updated on 27 November 2018

File name

Reg SPC DM 20_1 2ml IE.pdf

Reasons for updating

  • Improved presentation of SPC

Legal category:Product subject to medical prescription which may not be renewed (A)

Free text change information supplied by the pharmaceutical company

Improved presentation of SPC uploaded

Updated on 28 August 2018

File name

Reg_SPC_DM_20_1_2ml_IE_cl.pdf

Reasons for updating

  • Change to section 4.2 - Posology and method of administration
  • Change to section 4.3 - Contraindications
  • Change to section 4.4 - Special warnings and precautions for use
  • Change to section 4.5 - Interaction with other medicinal products and other forms of interaction
  • Change to section 4.6 - Pregnancy and lactation
  • Change to section 4.7 - Effects on ability to drive and use machines
  • Change to section 4.8 - Undesirable effects
  • Change to Section 4.8 – Undesirable effects - how to report a side effect
  • Change to section 4.9 - Overdose
  • Change to section 5.1 - Pharmacodynamic properties
  • Change to section 5.2 - Pharmacokinetic properties
  • Change to section 5.3 - Preclinical safety data

Legal category:Product subject to medical prescription which may not be renewed (A)

Free text change information supplied by the pharmaceutical company

The SPC has been updated as follows:

 

IE DM 025 - CDS revised to align with the information across the corticosteroid CDSs, and to fulfil PSUR commitment (to update the SPC with reference to Kaposi’s Sarcoma and to reformat section 4.8 of the SPCs.)

 

IE DM 029 - CDS revised to align with the information across the corticosteroid CDSs.

 

IE DM 031 - CDS was revised to include a warning for Pheochromocytoma.

 

IE DM 033 - CDS was updated to include warnings for benzyl alcohol.

 

IE DM 036 – CDS was updated to add statement re discouraging use of high doses of corticosteroids to treat traumatic brain injury.

 

IE DM 037 – CDS was updated to add warning concerning thrombosis including venous thromboembolism and to add thrombosis and pulmonary embolism as new ADRs.

 

IE DM 042 – SPC was updated in line with PRAC updates: methylprednisolone PSUSA-00002026-201411

 

IE DM 048 - CDS was updated to add a cautionary statement about use in patients with systemic sclerosis because an increased incidence of scleroderma renal crisis has been observed with corticosteroids, including methylprednisolone.

 

IE DM 049 - SPC was updated in line with PRAC updates: methylprednisolone PSUSA-00000449-201604

Updated on 11 July 2018

File name

Reg_SPC_DM_20_1_2ml_IE_cl.docx

Reasons for updating

  • Change to section 4.3 - Contraindications
  • Change to section 4.4 - Special warnings and precautions for use
  • Change to section 4.5 - Interaction with other medicinal products and other forms of interaction
  • Change to section 4.6 - Pregnancy and lactation
  • Change to section 4.7 - Effects on ability to drive and use machines
  • Change to section 4.8 - Undesirable effects
  • Change to Section 4.8 – Undesirable effects - how to report a side effect
  • Change to section 4.9 - Overdose
  • Change to section 5.1 - Pharmacodynamic properties
  • Change to section 5.2 - Pharmacokinetic properties
  • Change to section 5.3 - Preclinical safety data

Legal category:Product subject to medical prescription which may not be renewed (A)

Free text change information supplied by the pharmaceutical company

The SPC has been updated as follows:

 

IE DM 025 - CDS revised to align with the information across the corticosteroid CDSs, and to fulfil PSUR commitment (to update the SPC with reference to Kaposi’s Sarcoma and to reformat section 4.8 of the SPCs.)

 

IE DM 029 - CDS revised to align with the information across the corticosteroid CDSs.

 

IE DM 031 - CDS was revised to include a warning for Pheochromocytoma.

 

IE DM 033 - CDS was updated to include warnings for benzyl alcohol.

 

IE DM 036 – CDS was updated to add statement re discouraging use of high doses of corticosteroids to treat traumatic brain injury.

 

IE DM 037 – CDS was updated to add warning concerning thrombosis including venous thromboembolism and to add thrombosis and pulmonary embolism as new ADRs.

 

IE DM 042 – SPC was updated in line with PRAC updates: methylprednisolone PSUSA-00002026-201411

 

IE DM 048 - CDS was updated to add a cautionary statement about use in patients with systemic sclerosis because an increased incidence of scleroderma renal crisis has been observed with corticosteroids, including methylprednisolone.

 

IE DM 049 - SPC was updated in line with PRAC updates: methylprednisolone PSUSA-00000449-201604

Updated on 11 July 2018

File name

Reg HCP leaflet DM 20_1 PIL DM 20_1 IE cl.pdf

Reasons for updating

  • Change to section 2 - what you need to know - contraindications
  • Change to section 2 - what you need to know - warnings and precautions
  • Change to section 2 - interactions with other medicines, food or drink
  • Change to section 2 - pregnancy, breast feeding and fertility
  • Change to section 2 - driving and using machines
  • Change to section 4 - possible side effects
  • Change to section 4 - how to report a side effect
  • Change to section 5 - how to store or dispose
  • Change to section 6 - what the product contains
  • Change to section 6 - date of revision
  • Change to information for healthcare professionals
  • Correction of spelling/typing errors

Updated on 06 April 2017

Reasons for updating

  • New SPC for new product

Legal category:Product subject to medical prescription which may not be renewed (A)

Updated on 05 April 2017

File name

PIL_10820_294.pdf

Reasons for updating

  • New PIL for new product