Relvar Ellipta 184 micrograms/22 micrograms inhalation powder, pre-dispensed

*
Pharmacy Only: Prescription

Updated on 09 August 2024

File name

ie-spc-combined-relvar-184-issue21-draft1-master-clean.pdf

Reasons for updating

  • Change to Section 4.8 – Undesirable effects - how to report a side effect

Legal category:Product subject to medical prescription which may be renewed (B)

Free text change information supplied by the pharmaceutical company

Update to section 4.8 - Reporting of suspected adverse reactions

Updated on 09 August 2024

File name

ie-pl-combined-relvar-issue21-draft1-master-clean.pdf

Reasons for updating

  • Change to section 4 - how to report a side effect

Free text change information supplied by the pharmaceutical company

Update to section 4 - Reporting of side effects

Updated on 10 July 2024

File name

ieukni-spc-combined-relvar-184-issue20-draft1-clean.pdf

Reasons for updating

  • Change to section 5.1 - Pharmacodynamic properties
  • Change to section 10 - Date of revision of the text

Legal category:Product subject to medical prescription which may be renewed (B)

Free text change information supplied by the pharmaceutical company

SmPC section 5.1 update - Addition of study data

Updated on 19 September 2023

File name

ieukni-pl-combined-relvar-issue20-draft1-emc.pdf

Reasons for updating

  • Correction of spelling/typing errors

Updated on 24 July 2023

File name

ieukni-spc-combined-relvar-184-issue19-draft1.pdf

Reasons for updating

  • Change to section 4.2 - Posology and method of administration
  • Change to section 4.4 - Special warnings and precautions for use
  • Change to section 5.1 - Pharmacodynamic properties
  • Change to section 5.2 - Pharmacokinetic properties
  • Correction of spelling/typing errors

Legal category:Product subject to medical prescription which may be renewed (B)

Updated on 24 July 2023

File name

ieukni-pl-combined-relvar-issue20-draft1.pdf

Reasons for updating

  • Change to section 2 - what you need to know - warnings and precautions
  • Change to section 5 - how to store or dispose

Updated on 09 November 2021

File name

ieukni-pl-combined-relvar-issue18-draft1-compendia.pdf

Reasons for updating

  • Change to section 4 - how to report a side effect
  • Change to section 6 - date of revision
  • Change to other sources of information section

Updated on 09 November 2021

File name

ieukni-spc-combined-relvar-184-issue17-draft1-compendia.pdf

Reasons for updating

  • Change to section 4.8 - Undesirable effects
  • Change to Section 4.8 – Undesirable effects - how to report a side effect
  • Change to section 5.3 - Preclinical safety data
  • Change to section 10 - Date of revision of the text

Legal category:Product subject to medical prescription which may be renewed (B)

Updated on 18 February 2021

File name

ie-pl-relvar-issue17draft1-medie.pdf

Reasons for updating

  • Change to section 6 - manufacturer

Updated on 02 December 2020

File name

ie-spc-relvar-184-issue16-draft1.pdf

Reasons for updating

  • Change to section 2 - Qualitative and quantitative composition
  • Change to section 4.4 - Special warnings and precautions for use
  • Change to section 4.8 - Undesirable effects
  • Change to section 5.1 - Pharmacodynamic properties
  • Change to section 10 - Date of revision of the text

Legal category:Product subject to medical prescription which may be renewed (B)

Updated on 02 December 2020

File name

ie-pl-relvar-issue16draft1.pdf

Reasons for updating

  • Change to section 3 - how to take/use
  • Change to section 3 - overdose, missed or forgotten doses
  • Change to section 4 - possible side effects
  • Change to section 5 - how to store or dispose
  • Change to section 6 - what the product looks like and pack contents
  • Change to section 6 - marketing authorisation holder
  • Change to section 6 - date of revision
  • Change to other sources of information section

Updated on 02 January 2019

File name

ie-pl-relvar-issue15draft1-MED.IE.pdf

Reasons for updating

  • Change to section 4 - how to report a side effect
  • Change to section 6 - marketing authorisation holder
  • Change to section 6 - date of revision

Updated on 02 January 2019

File name

ie-spc-relvar-184-issue15-draft1-MED.IE.pdf

Reasons for updating

  • Change to Section 4.8 – Undesirable effects - how to report a side effect
  • Change to section 7 - Marketing authorisation holder
  • Change to section 10 - Date of revision of the text

Legal category:Product subject to medical prescription which may be renewed (B)

Free text change information supplied by the pharmaceutical company

Section 4.8: Splitting of pack to include just specific IE reporting details due to Brexit preparations
Section 7: Change of MAH address

Updated on 18 December 2018

File name

ukie-pl-relvar-issue14 - medicines compendium.pdf

Reasons for updating

  • Change to section 6 - date of revision
  • Change to other sources of information section

Updated on 24 September 2018

File name

ukie-pl-relvar-issue13draft2 for medicines compendia.pdf

Reasons for updating

  • Change to section 2 - what you need to know - warnings and precautions
  • Change to section 4 - possible side effects
  • Change to section 6 - date of revision

Updated on 24 September 2018

File name

ukie-spc-relvar-184-issue14-draft1 for medicines.ie.pdf

Reasons for updating

  • Change to section 4.8 - Undesirable effects
  • Change to section 10 - Date of revision of the text

Legal category:Product subject to medical prescription which may be renewed (B)

Free text change information supplied by the pharmaceutical company

SPC Section 4.8 - updated to include the addition of 'hyperglycaemia' as an adverse reaction

Updated on 07 August 2018

File name

ie-pl-relvar.pdf

Reasons for updating

  • Change to section 6 - date of revision
  • Improved presentation of PIL

Updated on 07 August 2018

File name

ie-spc-relvar184.pdf

Reasons for updating

  • Change to section 9 - Date of first authorisation/renewal of the authorisation
  • Change to section 10 - Date of revision of the text
  • Change to improve clarity and readability

Legal category:Product subject to medical prescription which may be renewed (B)

Updated on 27 June 2018

File name

ukie-spc-relvar-184-22-medicines IE.docx

Reasons for updating

  • Change to section 10 - Date of revision of the text
  • Removal of Black Inverted Triangle

Legal category:Product subject to medical prescription which may be renewed (B)

Free text change information supplied by the pharmaceutical company

Removal of Black Triangle Statement in both the SPC and PIL

Updated on 27 June 2018

File name

ukie-pl-relvar-92&184-22-medicines compendium.pdf

Reasons for updating

  • Removal of Black Inverted Triangle

Updated on 30 April 2018

Reasons for updating

  • New SPC for new product

Legal category:Product subject to medical prescription which may be renewed (B)

Updated on 13 March 2018

Reasons for updating

  • New SPC for new product

Legal category:Product subject to medical prescription which may be renewed (B)

Updated on 13 March 2018

Reasons for updating

  • Change to section 4.1 - Therapeutic indications
  • Change to section 5.1 - Pharmacodynamic properties
  • Change to section 10 - Date of revision of the text

Legal category:Product subject to medical prescription which may be renewed (B)

Free text change information supplied by the pharmaceutical company

SPC updated in sections 4.1 and 5.1 to include the indication extension for use in asthma.

Updated on 21 September 2017

File name

PIL_15900_855.pdf

Reasons for updating

  • New PIL for new product

Updated on 21 September 2017

Reasons for updating

  • Change to section 4.4 - Special warnings and precautions for use
  • Change to section 4.8 - Undesirable effects
  • Change to Section 4.8 – Undesirable effects - how to report a side effect
  • Change to section 10 - Date of revision of the text

Legal category:Product subject to medical prescription which may be renewed (B)

Free text change information supplied by the pharmaceutical company

Sections 4.4 and 4.8 has been updated in accordance with the wording proposed in the CMDh/PRAC recommendation on signals regarding ‘Blurred Vision’ and ‘Central Serous Chorioretinopathy’ as a class risk effect of corticosteroids.

Updated UK reporting details in S4.8 of SmPC to align with Appendix V requirements published by EMA.

Updated on 21 September 2017

Reasons for updating

  • Change to section 2 - what you need to know - warnings and precautions
  • Change to section 4 - possible side effects
  • Change to section 4 - how to report a side effect
  • Change to section 6 - date of revision

Updated on 31 May 2017

Reasons for updating

  • Change to section 4.5 - Interaction with other medicinal products and other forms of interaction
  • Change to section 10 - Date of revision of the text

Legal category:Product subject to medical prescription which may be renewed (B)

Free text change information supplied by the pharmaceutical company

SPC Section 4.5. Interaction with other medicinal products and other forms of interaction
Update to align to PRAC recommendation on drug interaction with corticosteroids

Updated on 31 May 2017

Reasons for updating

  • Change to section 2 - interactions with other medicines, food or drink
  • Change to section 6 - date of revision

Updated on 04 May 2017

Reasons for updating

  • Change to section 4.2 - Posology and method of administration
  • Change to section 4.4 - Special warnings and precautions for use
  • Change to section 4.8 - Undesirable effects
  • Change to section 5.1 - Pharmacodynamic properties
  • Change to section 10 - Date of revision of the text

Legal category:Product subject to medical prescription which may be renewed (B)

Free text change information supplied by the pharmaceutical company

Section 4.2 - Additional information regarding desiccant sachet

The SUMMIT submission:
-Addition of safety data to Section 4.4 and Section 4.8
-Addition of study design, mortality and CV composite endpoint data to Section 5.1.
-In addition, ‘bronchospasm’ was added to Section 4.8 List of Adverse Reactions, and there is a minor correction to the pharmacodynamics section of Section 5.1.

Updated on 03 May 2017

Reasons for updating

  • Change to section 4 - possible side effects
  • Change to section 6 - what the product looks like and pack contents
  • Change to section 6 - date of revision

Updated on 16 November 2016

Reasons for updating

  • Change to section 4.4 - Special warnings and precautions for use
  • Change to section 10 - Date of revision of the text

Legal category:Product subject to medical prescription which may be renewed (B)

Free text change information supplied by the pharmaceutical company

Section 4.4 Special warnings and precautions for use
Pneumonia in patients with COPD
Rewording text in line with Article 31 referral

Updated on 08 July 2016

Reasons for updating

  • Change to side-effects
  • Change to date of revision

Updated on 22 January 2016

Reasons for updating

  • Change of manufacturer
  • Change to date of revision

Updated on 23 December 2015

Reasons for updating

  • Change to section 4.2 - Posology and method of administration
  • Change to section 4.8 - Undesirable effects
  • Change to section 10 - Date of revision of the text
  • Correction of spelling/typing errors

Legal category:Product subject to medical prescription which may be renewed (B)

Free text change information supplied by the pharmaceutical company

 

Update to SPC

Update section 4.8 of the SPC in order to add muscle spasms as a new adverse reaction with the frequency Common.

Minor typographical amendment to COPD paediatric population text in section 4.2 of the SPC.

Updated on 22 December 2015

Reasons for updating

  • Change to side-effects
  • Change to date of revision
  • Change to MA holder contact details

Updated on 30 September 2015

Reasons for updating

  • Change to section 4.8 - Undesirable effects
  • Change to section 10 - Date of revision of the text

Legal category:Product subject to medical prescription which may be renewed (B)

Free text change information supplied by the pharmaceutical company

Update section 4.8 of the SPC in order to add anxiety and tremor as new adverse reactions with the frequency rare

Updated on 29 September 2015

Reasons for updating

  • Change to side-effects
  • Change to further information section
  • Change to date of revision

Updated on 06 July 2015

Reasons for updating

  • Change to section 4.4 - Special warnings and precautions for use
  • Change to section 4.8 - Undesirable effects
  • Change to section 10 - Date of revision of the text

Legal category:Product subject to medical prescription which may be renewed (B)

Free text change information supplied by the pharmaceutical company

Update section 4.4 - in order to amend warning regarding Cardiovascular effects
Update section 4.8 - addition of Palpitations and Tachycardia as new adverse reactions with the frequency rare

Updated on 01 July 2015

Reasons for updating

  • Change to warnings or special precautions for use
  • Change to side-effects
  • Change to date of revision

Updated on 08 January 2015

Reasons for updating

  • Change to section 4.8 - Undesirable effects
  • Change to section 5.1 - Pharmacodynamic properties

Legal category:Product subject to medical prescription which may be renewed (B)

Free text change information supplied by the pharmaceutical company

Section 4.8 – Addition of hypersensitivity adverse event

Section 5.1 – Typo updates

Updated on 06 January 2015

Reasons for updating

  • Change to side-effects
  • Change to date of revision

Updated on 05 January 2015

Reasons for updating

  • Change to side-effects

Updated on 10 June 2014

Reasons for updating

  • Change to warnings or special precautions for use
  • Change to date of revision

Updated on 03 February 2014

Reasons for updating

  • Change to Section 4.8 – Undesirable effects - how to report a side effect

Legal category:Product subject to medical prescription which may be renewed (B)

Free text change information supplied by the pharmaceutical company

Changes to:

 

 

Section 4.8 - Undesirable effects

 

Updated on 29 January 2014

Reasons for updating

  • Change to side-effects

Updated on 09 December 2013

Reasons for updating

  • New SPC for new product

Legal category:Product subject to medical prescription which may be renewed (B)

Free text change information supplied by the pharmaceutical company

None provided

Updated on 26 November 2013

Reasons for updating

  • New PIL for new product