Spevigo 450 mg concentrate for solution for infusion

*
Pharmacy Only: Prescription
  • Company:

    Boehringer Ingelheim Limited
  • Status:

    Updated
  • Legal Category:

    Product subject to medical prescription which may be renewed (B)
  • Active Ingredient(s):

    This medicinal product is subject to additional monitoring.

    *Additional information is available within the SPC or upon request to the company

Updated on 10 December 2024

File name

S11a-EU-SPC-4.pdf

Reasons for updating

  • Change to section 10 - Date of revision of the text

Legal category:Product subject to medical prescription which may be renewed (B)

Free text change information supplied by the pharmaceutical company

Annual renewal of the conditional MA; no updates were made to the SmPC text, only date of revision 

Updated on 11 October 2024

File name

X-0006G -PIL - Spevigo.pdf

Reasons for updating

  • Change to section 1 - what the product is used for
  • Change to section 2 - use in children and adolescents
  • Change to section 3 - how to take/use
  • Change to section 4 - possible side effects
  • Change to section 6 - date of revision
  • Change to information for healthcare professionals

Updated on 11 October 2024

File name

S11a-EU-SPC-3 medicines.ie.pdf

Reasons for updating

  • Change to section 4.1 - Therapeutic indications
  • Change to section 4.2 - Posology and method of administration
  • Change to section 4.4 - Special warnings and precautions for use
  • Change to section 4.5 - Interaction with other medicinal products and other forms of interaction
  • Change to section 4.6 - Pregnancy and lactation
  • Change to section 4.8 - Undesirable effects
  • Change to section 4.9 - Overdose
  • Change to section 5.1 - Pharmacodynamic properties
  • Change to section 5.2 - Pharmacokinetic properties
  • Change to section 6.6 - Special precautions for disposal and other handling
  • Change to section 10 - Date of revision of the text

Legal category:Product subject to medical prescription which may be renewed (B)

Free text change information supplied by the pharmaceutical company


Section 4.1 Therapeutic indications: now includes the treatment of flares in GPP in adolescents as monotherapy

Section 4.2 Posology and method of administration: updated to include reference to the pre-filled syringe; revised dosing information for adolescents including adolescents weighing ≥ 30 and < 40 kg; new heading ‘Special populations’.

Section 4.4 Special warnings and precautions for use: update to information relating to Hypersensitivity and infusion-related reactions; Re-treatment; Immunisations

Section 4.5 Interaction with other medicinal products and other forms of interaction: updated wording

Section 4.6: Fertility, pregnancy and lactation: updated wording for breastfeeding

Section 4.8 Undesirable effects: update to summary and Table 1; update to wording on infections; text on immunogenicity removed; text on paediatric populations added.

Section 4.9 Overdose: additional text

Section 5.1 Pharmacodynamic properties: main changes, update to Table 2 for Effisayil 1; inclusion of information from Effasayil 2; text on immunogenicity added; paediatric population statement updated.

Section 5.2 Pharmacokinetic properties: updated information

Section 6.6 Special precautions for disposal and other handling: update to the handling instructions

Section 10 Date of revision of the text: updated to 25 September 2024


Updated on 01 November 2023

File name

Spevigo pil text MAA.pdf

Reasons for updating

  • New PIL for new product

Updated on 01 November 2023

File name

S11-EU-SPC-2.pdf

Reasons for updating

  • New SPC for new product

Legal category:Product subject to medical prescription which may be renewed (B)